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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7b1585625f9c3e637a233a502ffa5c604e0f9030f7e4eaf358ebb6b317884c' 
  AND token = 'gj3XHSiZEm2+AgV04PMj7zDH2ZnEZVh4kLcd95gH9R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}