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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b976d227443622e1315749e35f06c57cbaf908d08737daf69e8f9180d0bac5a5' 
  AND token = '3sjYCGxn0XsyvFXOXR5/XThi5PM2hpc0IwnYB97OSsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}