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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38f25c6a34b25a8d2536a08c04c4969bb0a2958e13ccd2a003f0daace4b0261' 
  AND token = 'PExqb2WuGqSPerhE49t93ZtFRnQ1C9X/Nc6EPhpMoRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}