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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258973ceb821573fa76d95d0756b65fd40fa21d2bf31fe46ea9e11e106718ace' 
  AND token = 'cVovfhFuznblRayNKLlmgHLcf6lBvzle89ZhzgS1P/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}