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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0afcc5f84c02f20a69b3995701f742e56e7777fbd3c05c8bd7fc8baa1cd66538' 
  AND token = 'gkmU3R20kY4pHYfl5sRfBfG64gfWMKwDp0AvSgNBjhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}