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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e8077b46418680ce9622d5b74cb926a3ec7d2bb3f935f649c993cf9e60374b' 
  AND token = 'rFgO5sXoqSe8l7kjgeWaZN+U3nlBZAZHfdyo6vXc9r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}