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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43eac8261a061d4e0eeb9440608ec4522c4448a5a70b6bafac7e3b3faf1b0362' 
  AND token = 'mpBoWVbrxJmWrbQszAJC2EuM2ALzZ9L3Xz3jt2LsUDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}