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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edfa86e81047f58a0cf8042d4ccce1eb9067ba57be6e481e4babbbf11ee2a882' 
  AND token = 'e+qMFAFx0QTpxBEQRjfuctwGdAcvyHoKO/VRDMA/WtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}