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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0fd7050acd983892d4ee96a7a762906d3ba84c7b2027eb9e617a693cb897c6' 
  AND token = 'DTBW4ZIr+U92vMI0VVhuVoDicrpbLUzFTKDC5Dwyubs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}