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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7392eaf6bf08cb167f59018f2fc8784a8640f556888726c19be287ef138bc7d' 
  AND token = 'ytYWtt4kSmsSBLMPGSoYu+7K/0cWJTSRlVucMkcdXlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}