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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680e5e1d1fe834057773a1ead0cef3a587904061a6b87c6129928817a23282d0' 
  AND token = 'C1QRv/nXiIV4UuGMQiMEx5MRQcBMFol5qRNAQi1ZiKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}