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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '245ce072fda4bccd71c88baf69dae5d7d4ecda466250e9b977b776af7f3b7a34' 
  AND token = 'fqb9M0taGw/LHUCP7mFkYxmPp8it8HCSPaujw/TjzhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}