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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e86aac68d2ef4b2266a14365c139ac2e0ca749af9ea6bec19c7358b34bf2078' 
  AND token = 'd9CF0maWSAuv2kpBH6lIL/PQhKOjfoKMKYxkZU9IMEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}