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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e52038dc1cf5ee8d032b6fbf5be49f764d4700687b0e870d38d694bdee505d0' 
  AND token = 'pQ9Gbky5SHki2E25Z0BpQI85mUklSRWaQCjXB7tCcB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}