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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5266c03c4168b2f473bd31ce2ce9a9016e353c59ba67a0ac4845359b2eed3262' 
  AND token = 'vKE/QXc5qQ8O5iqIdLq0vshcSiyDK3qENiwv1PjLsP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}