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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4792ca24e32f9f394beb2e3de514b6dbbf9cfce11968633930d08fad6a74a322' 
  AND token = 'olgHmLX36mfhEE5ydc+SBHZpOsLZVS+/300e5D4ewgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}