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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7d0d7c99f6aa957e1ad62ee99e1908ef63e94c621fc522638542d22d29fc4c' 
  AND token = 'dbjbYM28aHcgzrT05/CsDrrQ8tSLjAgD4Ugj8JkBrWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}