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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549a36c5ebe70deceff362cd9f662804e91b4b72802502756538dc1c39ddc9b1' 
  AND token = 'lsnuxBGHYi51fBcp7FxsR+9Zma2b5Y9SNSj0pmLZd6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}