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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37cc9d19f55c12fc6ca5f13de646aed7844d6f3f5c52704c7aea5cb7a11259e7' 
  AND token = '4bEHXCSMgT38TlZ5KSm1+uBSwl2Y2vIIeiwECvmx60g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}