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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f499d35d723c9ecc9f5bcab3e746dde53c645d5de32f4afa371eae9c0b4011f' 
  AND token = 'kwfqVWzDd6yjcGbiaox4UhnbzK7xaW4urD3q1CNE2u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}