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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42c4b777bab203dca6853853703e27c9f2d874d5adfa945d9ff44e42a9371f7' 
  AND token = '12fi64DA1xzpRxgf5MFfGo6CwTamQmCErvrKz0sA2Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}