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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '788190196bc18e97baa78da2fd0acc1c6bf6e3144dd2f1bfd2c1bf892c4ae69c' 
  AND token = 'JI9eFYtwo2+czTCiJcYKdwA5w+91j6CVQ1Ox9nAQqK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}