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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc743d40d9f2c46257a1e1fc654cd11a68720b8087ac282996b4a4855b698186' 
  AND token = 'siaCk4mLSiFIfCpF7+msDMFEYjivNlwzmfHAi0Z22es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}