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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41c8e97687e9e86e75f8a9b0b4d7e4524db58b2f573f30954a4125b27a9a645' 
  AND token = 'l4BpoHp1VoO9uVEKr1ZYehKCNhKUTdY85fBp2MJPfRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}