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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a7e42e2d16f813e0e76be82f10167b8902cb3cf96c20a9d6c75f07a587817b' 
  AND token = '2FOIVGHXB9fxUMQf0yCtRWG+cCnNDLl9sEIEyLQu0GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}