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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a5e7e17365dad72f9d7e2bc36b6fd411495562aa7122ae38e188bf4d639a944' 
  AND token = '+qSDNkW4yt7tg64oTdPiwvmz28XmtBXKYj6ij886Wf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}