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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d968f34b34d8220d63c684fe48539a4f13bd4cca14a5e7a1b5c78a974540f37' 
  AND token = 'LiFqyjt1rMnfRdUpYFL6qiTcps2u6ChHrgppfjlv5P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}