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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed8ff6540bf8f74e8d7289e29bd5d2771e474ae6c1e9f323d0a271f903b1abe' 
  AND token = 'IoJeSGVWUluRlj4NnZ3PfJ/TpVdNkBa6L0qeBrJjPAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}