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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1386ecf403d15c72234b11782e9dfa90e104c1f178536e2c06c23c2e2fc673a' 
  AND token = 'IvL9xoRljmd/RLjPXrNly3JfByWxjKheHfU+iTL5S6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}