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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189bddbfda35571812f4791ff7f6195884e17f6e4561fc25774ae1872cc618cb' 
  AND token = '7QTFrt34SGA4BiHWUcQu1NPURoIiMdeHG6r6TJXgkqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}