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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aae609666207f9e09bf05645c41e024265f7127e4ee8c3658c749ae3d0deaa8' 
  AND token = 'lkDELrdFlQ3ZV3+LQgRT8OvNCBzMU9lUqhuHHzQeVu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}