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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322ca447ff19ab2ab0707a2ffb1d383e0bbfbf877fbc6dab8f946a39fa448d3f' 
  AND token = 'nwWlFujrwBzSSGUPJWRhMObJ6cMhGFSG1L83eSoHFts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}