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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81d5332d8ab162f33b041705fc9b30504c058c7595a934734cc42d9373f27af' 
  AND token = 'WmkKWDtkS+b1SlnZGhgecWsO0UuknHk9q5GuVTQB8Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}