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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1dd111a9d64d2467f02f1bc4b1495fbde0132c0de68b867e5cf8a2b2c134cdd' 
  AND token = 'HMy/WYNlpT6Znq96LtDq0ekkxMOS7HEGzMVanomDunU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}