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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6c0bada05a5f6511c7ea6fe12476a574f2353beed77bd8cf2c2aecc8b21a0d' 
  AND token = 'G9OjsDjZMj8Smdpp5pL1t//z8RZzn/H1WEn1KXr66AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}