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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57223b841bab712be366698334c7c8b7463e563a4a1ce486465f221a34261e4e' 
  AND token = 'Vu9A8/EcrSl4Bcrq+OvApXCCkJXIoWc5QCVoR8zdM6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}