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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4903be03d2c1c559e57cfb16815bcb71fbd1f99fd3207896468e23feb34dcb97' 
  AND token = 'PDY9a7C2sNNUwAF2KW6tKvvmwQ16nPkrDK4AzO2UxGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}