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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7133335bf183bff1d4a375a3a78a6ea06642ad3652fe8d2ceb2a1980820876f' 
  AND token = '7NkbK/xGQLGjyBiWmkUbhMKdJLihnABCKcf+xGJhdJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}