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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad00aa589a89b486d67b7f3b220a927a91bf4cfb6f43934366cf0b96addf3f32' 
  AND token = 'ZXd6QOmzstYcORe9YyxUbeHsuKE3/pPmiZHvQKmuy5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}