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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc8dc2e5a84e2ec2ac14d2ba95711af1e254d7327cdde8c159675725a7f643a' 
  AND token = 'zEEuak+rvlKtQjuUEe2t/9eJYk3jd7SbN/L5fgZAjsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}