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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164aa76d35a3f593855f60848e769a5b80dcb963ec5502d7632401add16a607d' 
  AND token = 'xp3Y8sBqV5vMMRdDkKb5ECUXI5fP6MyYbaKYqkvDbDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}