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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f5dd4e0b95e01549fe4d0e66e6ec1dba47b86e6f10912113fe8b46f3d4bc60' 
  AND token = 'tpvjFJQkXTQP+M/P2KYK6gxqoxjuSXTwlvpd1YVpAXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}