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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '044658afe0303b56730a2da8f950e11e44b977ff62c4c2863134c088983c5277' 
  AND token = '0hMamSlBvePCqkd1mjKmSsIrSiQqp3izfqBgFnFg2jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}