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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d38114ff08d5a6eb8803c0fd7d828cc05b344b19d8ee095a7c8e3c965fcad4' 
  AND token = 'gi4q+6lRpESXvDv5FRBfG4hcue0mC1zD1Px23opxGv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}