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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7d83432aedc1f11bce60008e10f0154fe66cff126af492af191009e7a15e2fc' 
  AND token = 'QS4wdAEsHw06V0hEz9zfXIyod5pA8msfJHkWVXhQL78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}