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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e573096e49dfb56fb590431d21e3a41f41b8bb799c5680d4212b49fb6056340' 
  AND token = 'nI627+BAvBn4lBB8/xhjBKXmik40W57XhdN3q9ti19o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}