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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0f48841d05500ccabe89d2b1b39e94d23dabfedc2311de08e4651ba1991904' 
  AND token = 'PrHCZeMlaepcsBYi0XgXaQwc2JM+d4x1/1w5YZ5wp+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}