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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5894b204d7ecc0a1a834c090e296d5239dd1be72ca749c1047b195be95b5a1' 
  AND token = 'IBSihtuxfmPS0zuLUiPYqGaCbwNuFOoYR+Q3i/GqA/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}