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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c50342c492d5efe880ef79ff879a9c3029b6e58310f7cf0e3182346dc074b04' 
  AND token = 'J8/Pkpd1YXlW+67lnapsr/DmDQCZSMDWwC/+PaAbxBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}