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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10e6dc84bfdd1e66b172e5fb2b75ef4369e6aff4db407e92711e6fc5a108d0e' 
  AND token = 'AU0aYEO/6y5hR4L4tPnylbUorKQJCEFvGx29Pd4TjvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}